|本期目錄/Table of Contents|

[1]王黎曌,薛永來,高璐,等.納米氧化銅對斑馬魚甲狀腺系統的幹擾效應[J].江蘇農業科學,2019,47(14):202-205.
 Wang Lizhao,et al.Interference effects of CuO NPs on thyroid system in zebrafish[J].,2019,47(14):202-205.
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納米氧化銅對斑馬魚甲狀腺系統的幹擾效應(PDF)
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《江蘇農業科學》[ISSN:1002-1302/CN:32-1214/S]

卷:
第47卷
期數:
2019年第14期
頁碼:
202-205
欄目:
畜牧獸醫與水産蠶桑
出版日期:
2019-08-10

文章信息/Info

Title:
Interference effects of CuO NPs on thyroid system in zebrafish
作者:
王黎曌 薛永來 高璐 杜道林
江蘇大學環境與安全工程學院,江蘇鎮江 212013
Author(s):
Wang Lizhaoet al
關鍵詞:
納米氧化銅斑馬魚甲狀腺濾泡激素基因
Keywords:
-
分類號:
S941.91;X174
DOI:
-
文獻標志碼:
A
摘要:
目前納米技術發展和應用以指數形式快速增長,納米氧化銅(copper oxide nanoparticles,CuO NPs)因在吸光性、磁性、化學催化和熱傳導等方面具有獨特的優勢而得到廣泛應用,近期關于CuO NPs對細胞、動物胚胎和植物的毒性報道日益增多,但是關于CuO NPs對魚類甲狀腺系統的報道相對較少。因此,本試驗選用斑馬魚作爲研究對象,從細胞形態、激素水平和基因層面研究了納米氧化銅對斑馬魚甲狀腺系統造成的幹擾效應。結果表明,CuO NPs可損傷甲狀腺濾泡結構,改變上皮細胞形態,誘導甲狀腺激素T3和T4上升並且造成代謝酶編碼基因ugt1ab的表達下調。
Abstract:
-

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備注/Memo

備注/Memo:
收稿日期:2018-05-02
基金項目:國家自然科學基金(編號:31100379、31601380);江蘇大學高級人才基金(編號:10JGD056)。
作者簡介:王黎曌(1991—),女,江蘇鹽城人,碩士研究生,主要研究方向爲環境毒理學。E-mail:wanglizhao1111@163.com。
通信作者:薛永來,博士,副教授,主要研究方向爲環境毒理學、環境生物學。E-mail:xueyonglai@sina.com。
更新日期/Last Update: 2019-07-20